Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetrafluoroethylene → Ethyl 1-(4-ethoxyphenyl)-2,2,3,3-tetrafluorocyclobutane carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetrafluoroethylene | HCID 8301 | — |
| 반응물 | Benzeneacetic acid, 4-ethoxy-alpha-methylene-, ethyl ester | HCID 6454764 | — |
| 촉매 | (+-)-alpha-Pinene | HCID 6654 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | Ethyl 1-(4-ethoxyphenyl)-2,2,3,3-tetrafluorocyclobutane carboxylate | HCID 13239546 | 75% |
반응 단계
2-(4-ethoxyphenyl)propenoic acid ethyl ester (13.2 g) was mixed with benzene (7.5 ml), α-pinene (2 drops) N-ethyldiisopropyl amine (2 drops) and tetrafluoroethylene (15.5 ml) and heated to 150°-155° for 24 hours then 155°-160° C. for 17 hours. After evaporation of volatile materials the residue (16.6 g) was dissolved in dichloromethane and chromatographed on a column of silica gel to give the ester as a colourless oil 14.5 g (75%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04235926 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-cb3cc7b1544641ca9e96a082ef43d9ed |
| 출처 메모 | uspto-grants-1980_11 |