Benzene → 2,2-Dimethyl-3-heptanoyl oxazolidine

HRID 225228

반응식

HRID 225228 반응식
C1C=CC=CC=1.[CH3:7][C:8]1([CH3:13])[NH:12][CH2:11][CH2:10][O:9]1.C(N(CC)CC)C.[C:21](Cl)(=[O:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>O>[CH3:7][C:8]1([CH3:13])[N:12]([C:21](=[O:28])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH2:11][CH2:10][O:9]1

참가 물질

6

반응물 4

HCID 241Benzene2회HCID 8471TriethylamineHCID 17313Heptanoyl chlorideHCID 5506972,2-Dimethyl-oxazolidine

생성물 1

HCID 129067982,2-Dimethyl-3-heptanoyl oxazolidine

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Sixteen and one-half (16.5 ml.) milliliters of a benzene solution containing 4.6 g. of 2,2-dimethyl oxazolidine was added to 50 ml. of benzene and 4.1 g. of triethylamine. To this mixture 6 g. of n-heptanoyl chloride was added dropwise with stirring and cooling in an ice bath. The mixture was poured into water and the benzene layer extracted, dried over magnesium sulfate and the benzene removed under vacuum. Yield was 7.5 g. of an oil, nD30 =1.4598.

후처리

  1. temperaturecooling in an ice bath
  2. extractionthe benzene layer extracted
  3. dry with materialdried over magnesium sulfate
  4. customthe benzene removed under vacuum

출처 및 근거

ORD 기록
ord-39e1f6b09b71420ca16b1f1bbe89257c
출처 데이터셋
uspto-grants-1980_11
특허 번호
US04236011

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