2-(azidomethyl)-4-chloro-N-methylbenzamide → 2-(aminomethyl)-N-methylBenzamide
반응식
[N:1]([CH2:4][C:5]1[CH:14]=[C:13](Cl)[CH:12]=[CH:11][C:6]=1[C:7]([NH:9][CH3:10])=[O:8])=[N+]=[N-]>C(O)C>[NH2:1][CH2:4][C:5]1[CH:14]=[CH:13][CH:12]=[CH:11][C:6]=1[C:7]([NH:9][CH3:10])=[O:8]참가 물질
3
실험 절차
2-(Azidomethyl)-4-chloro-N-methylbenzamide (0.88 g, 3.94 mmol) was dissolved in ethanol (25 mL), degassed, treated with 10% Pd on carbon (80 mg), and put under one atmosphere of hydrogen. After one hour the reaction was filtered through Celite, and concentrated in vacuo to afford 2-(aminomethyl)-N-methylbenzamide as a white solid.
후처리
- customdegassed
- additiontreated with 10% Pd on carbon (80 mg)
- filtrationAfter one hour the reaction was filtered through Celite
- concentrationconcentrated in vacuo
출처 및 근거
- ORD 기록
- ord-65161268a57943528c12f6cddeccd3e2
- 출처 데이터셋
- uspto-grants-2008_01
- 특허 번호
- US07323460B2
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