Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3',4'-Dimethyl-3-dimethylaminoacrylophenone → Ethyl 7-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3',4'-Dimethyl-3-dimethylaminoacrylophenone | HCID 54311844 | — |
| 반응물 | HCID 178469928 | HCID 178469928 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | Ethyl 7-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate | HCID 11346960 | — |
반응 단계
A mixture of 4.06 g. of 3',4'-dimethyl-3-dimethylaminoacrylophenone and 3.10 g. of ethyl 3-aminopyrazole-4-carboxylate in 25 ml. of glacial acetic acid is refluxed for 6 hours. The desired compound is recovered as in previous examples except that the compound as first observed is amorphous and then crystallizes on standing in the crystallization solvent, m.p. 187°-188° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04236005 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-62e38a1efe7b44b5b4f7de60b49e8639 |
| 출처 메모 | uspto-grants-1980_11 |