Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | (-)-alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester | HCID 53644499 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | alpha-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid | HCID 23329768 | — |
반응 단계
(-)-α-Amino-4-hydroxy-3-(methoxymethyl)benzeneacetic acid methyl ester is dissolved in aqueous 1 N sodium hydroxide and the solution is stirred at 40°-50° C. for 1 hour. The solution is acidified with 6 N hydrochloric acid to a pH of 7. Evaporation of the solvent gives the title compound in a 90% overall yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04236002 |
| 출처 데이터셋 | uspto-grants-1980_11 |
| ORD ID | ord-af841033f58e4f8598fea6d220f4ff2f |
| 출처 메모 | uspto-grants-1980_11 |