1-[2-Hydroxy-4,6-bis(methoxymethoxy)phenyl]ethanone → 4-Methoxybenzaldehyde

HRID 2254263

반응식

HRID 2254263 반응식
O[C:2]1[CH:7]=[C:6]([O:8][CH2:9]OC)[CH:5]=[C:4](OCOC)[C:3]=1[C:16](=[O:18])C>C(O)C>[CH3:9][O:8][C:6]1[CH:7]=[CH:2][C:3]([CH:16]=[O:18])=[CH:4][CH:5]=1

참가 물질

3

반응물 1

HCID 108796971-[2-Hydroxy-4,6-bis(methoxymethoxy)phenyl]ethanone

생성물 1

HCID 312444-Methoxybenzaldehyde수율 114.5%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

In 45 ml of ethanol were dissolved 6.00 g of the 2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone obtained in Production Example 11 and 3.65 g of the p-methoxybenzaldehyde obtained in Production Example 25, and the solution was cooled to 0° C. and 55 ml of a saturated solution of potassium hydroxide in ethanol was added to the solution. The mixture was stirred for 24 hours. After the reaction, the reaction liquid was diluted with water and neutralized with 6 N hydrochloric acid, and the formed precipitate was recovered by filtration to obtain 8.17 g (yield=86.3%) of 2'-hydroxy-4,4',6'-tris(methoxymethoxy)chalcone.

출처 및 근거

ORD 기록
ord-6093b9f0ae964a008d8813b491a5678f
출처 데이터셋
uspto-grants-1993_08
특허 번호
US05234951

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