Ethyl 3-(furan-2-yl)benzoate → [3-(2-Furyl)phenyl]methanol

HRID 2254439노트

반응식

HRID 2254439 반응식
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:7]=[C:8]([CH:14]=[CH:15][CH:16]=1)[C:9](OCC)=[O:10].[H-].[Al+3].[Li+].[H-].[H-].[H-]>C(OCC)C>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:7]=[C:8]([CH:14]=[CH:15][CH:16]=1)[CH2:9][OH:10]

참가 물질

4

반응물 2

HCID 19744763Ethyl 3-(furan-2-yl)benzoateHCID 21226445Aluminium lithium hydride

생성물 1

HCID 11116545[3-(2-Furyl)phenyl]methanol수율 83%

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

Ethyl 3-(2-furyl)benzoate J. Chem. Soc., (B), 1971, 2305] was dissolved in 5 ml of anhydrous ethyl ether, and with stirring under ice cooling, 23 mg of lithium aluminum hydride was added. The mixture was stirred for 40 minutes. After the reaction, the reaction mixture was extracted by adding water and ethyl ether. The extract was worked up in a customary manner to give 170 mg (yield 83%) of 3-(2-furyl)benzyl alcohol.

후처리

  1. stirringThe mixture was stirred for 40 minutes
  2. customAfter the reaction
  3. extractionthe reaction mixture was extracted
  4. additionby adding water and ethyl ether

출처 및 근거

ORD 기록
ord-4554c789d62e45aebdcbd8fde12e3df5
출처 데이터셋
uspto-grants-1993_08
특허 번호
US05234946

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