Diethyl Ether → 2-(2-Furyl)benzyl chloride

반응식

O1C=CC=[C:2]1[C:6]1[CH:7]=[C:8]([CH:11]=[CH:12][CH:13]=1)CO.S(Cl)([Cl:16])=O.[CH2:18]([O:20][CH2:21][CH3:22])[CH3:19]>>[O:20]1[CH:21]=[CH:22][CH:19]=[C:18]1[C:13]1[CH:12]=[CH:11][CH:8]=[CH:7][C:6]=1[CH2:2][Cl:16]

참가 물질

반응물 3

HCID 3283Diethyl Ether

HCID 24386Thionyl Chloride

HCID 11116545[3-(2-Furyl)phenyl]methanol

생성물 1

HCID 197446022-(2-Furyl)benzyl chloride

실험 절차

160 mg of the resulting alcohol compound was dissolved in 3 ml of anhydrous ethyl ether. Thionyl chloride (73 microliters) was added, and under ice cooling, the mixture was stirred for 3 hours. After the reaction, the reaction mixture was washed with a saturated aqueous solution of sodium chloride and 5% sodium hydrogen carbonate to give an ethyl ether solution of the captioned compound. It was used directly in the reaction of Example 58.

후처리

customAfter the reaction
washthe reaction mixture was washed with a saturated aqueous solution of sodium chloride and 5% sodium hydrogen carbonate
customto give an ethyl ether solution of the captioned compound
customIt was used directly in the reaction of Example 58

출처 및 근거

ORD 기록: ord-c56edbb658dd4840b4c7c5286e3f2558
출처 데이터셋: uspto-grants-1993_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05234946

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