Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(p-Cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridine → Fadrozole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(p-Cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridine | HCID 15294718 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Fadrozole | HCID 59693 | — |
반응 단계
A solution of 1.6 g of 5-(p-cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridine in 50 ml of ethyl acetate is hydrogenated at atmospheric pressure with 0.2 g of 5% palladium on charcoal until the theoretical uptake of hydrogen is complete. The catalyst is filtered, and the solvent evaporated to yield the title compound, m.p. 117°-118°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05428160 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-876dfb1f07c84d42a9f8c445f8faa829 |
| 출처 메모 | uspto-grants-1995_06 |