1,4-Dioxane hydrochloride → [4-(Hydroxymethyl)piperidin-4-yl]methanol hydrochloride

HRID 225474노트

반응식

HRID 225474 반응식
C(OC([N:8]1[CH2:13][CH2:12][C:11]([CH2:16][OH:17])([CH2:14][OH:15])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:18].O1CCOCC1>CO>[ClH:18].[NH:8]1[CH2:13][CH2:12][C:11]([CH2:16][OH:17])([CH2:14][OH:15])[CH2:10][CH2:9]1

참가 물질

4

반응물 2

HCID 204431481,4-Dioxane hydrochlorideHCID 21955203Tert-butyl 4,4-bis(hydroxymethyl)piperidine-1-carboxylate

생성물 1

HCID 67199428[4-(Hydroxymethyl)piperidin-4-yl]methanol hydrochloride

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A mixture of (1-tert-butoxycarbonylpiperidine-4,4-diyl)dimethanol, 4M HCl-dioxane solution and MeOH was stirred for two hours at room temperature to give piperidine-4,4-diyldimethanol hydrochloride.

출처 및 근거

ORD 기록
ord-6fea63b203394a278be5f892bbb08b00
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07557112B2

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