tert-Butyl 5-iodoisoindoline-2-carboxylate → 5-Isopropoxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

HRID 225584노트

반응식

HRID 225584 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13](I)[CH:14]=2)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]>CC(O)C>[C:1]([O:5][C:6]([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([O:5][CH:1]([CH3:3])[CH3:2])[CH:14]=2)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 1

HCID 57753580tert-Butyl 5-iodoisoindoline-2-carboxylate

생성물 1

HCID 577533995-Isopropoxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

시약·촉매·용매 1

HCID 3776Isopropanol용매

실험 절차

Prepared in analogy to Example A6(a) from 5-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester (Example A38(b)) and 2-propanol. White solid. MS (m/e): 222.1 ([M+H−Me2C═CH2]+, 100%).

출처 및 근거

ORD 기록
ord-f3ea4c63e72848aa970d2a6a5b4d5263
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07557114B2

반응 노트

불러오는 중…