3-Oxa-8-azabicyclo(3.2.1)octane hydrochloride → HCID 57753423, 화합물

HRID 225623

반응식

HRID 225623 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13](I)[CH:14]=2)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl.[CH:19]12[NH:26][CH:23]([CH2:24][CH2:25]1)[CH2:22][O:21][CH2:20]2>>[C:1]([O:5][C:6]([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([N:26]3[CH:19]4[CH2:25][CH2:24][CH:23]3[CH2:22][O:21][CH2:20]4)[CH:14]=2)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 534011293-Oxa-8-azabicyclo(3.2.1)octane hydrochlorideHCID 57753580tert-Butyl 5-iodoisoindoline-2-carboxylate

생성물 1

HCID 57753423HCID 57753423, 화합물

실험 절차

Prepared in analogy to Example A3(d) from 5-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester (Example A38(b)) and 3-oxa-8-azabicyclo[3.2.1]octane hydrochloride. Yellow oil. MS (m/e): 331.4 ([M+H]+, 100%).

출처 및 근거

ORD 기록
ord-44a0b02d814c404fb024ff380e83f53f
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07557114B2

연결된 노트

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