3,3,3-Trifluoro-1-propanol → HCID 57753429, 화합물

HRID 225683

반응식

HRID 225683 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13](I)[CH:14]=2)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[F:18][C:19]([F:24])([F:23])[CH2:20][CH2:21][OH:22]>>[C:1]([O:5][C:6]([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([O:22][CH2:21][CH2:20][C:19]([F:24])([F:23])[F:18])[CH:14]=2)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 1375123,3,3-Trifluoro-1-propanolHCID 57753580tert-Butyl 5-iodoisoindoline-2-carboxylate

생성물 1

HCID 57753429HCID 57753429, 화합물

실험 절차

Prepared in analogy to Example A6(a) from 5-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester (Example A38(b)) and 3,3,3-trifluoropropanol. Off-white solid. MS (m/e): 276.3 ([M+H—Me2C═CH2]+, 100%)

출처 및 근거

ORD 기록
ord-0a6916a37a9c47f4ab4767b6eeee94e5
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07557114B2

연결된 노트

불러오는 중…