참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | 2-Propenamide, 3-phenyl- | HCID 12135 | — |
| 반응물 | Methyl 4-bromo-3-oxopentanoate | HCID 9815681 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 86594851 | HCID 86594851 | 11.4% |
반응 단계
Cinnamamide (0.5 g) and methyl 4-bromo-3-oxopentanoate (0.71 g) were dissolved in N,N-dimethylformamide (2.5 ml) and the mixture was stirred 100° C. for 15 h. Ethylacetate (50 ml) was added, and the mixture was washed with water (100 ml) and then with saturated brine (100 ml), and dried (Na2SO4). Ethyl acetate was evaporated under reduced pressure and the obtained residue was purified by column chromatography to give the title compound (0.1 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07557123B2 |
|---|
| 출처 데이터셋 | uspto-grants-2009_07 |
|---|
| ORD ID | ord-c173fd40267040489bc68ac8304425c8 |
|---|
| 출처 메모 | uspto-grants-2009_07 |
|---|
