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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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HCID 131720122, 화합물 → HCID 131720123, 화합물

HRID 2258025
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HRID 2258025 반응식
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]([C:20]3[CH:28]=[CH:27][C:23]4[O:24][CH2:25][O:26][C:22]=4[CH:21]=3)[CH:11]([N+:17]([O-])=O)[C:12]([O:14][CH2:15][CH3:16])=[O:13])=[CH:9][C:4]=2[O:3][CH2:2]1.[H][H]>C(OCC)(=O)C.CO.[Pd]>[NH2:17][CH:11]([CH:10]([C:8]1[CH:7]=[CH:6][C:5]2[O:1][CH2:2][O:3][C:4]=2[CH:9]=1)[C:20]1[CH:28]=[CH:27][C:23]2[O:24][CH2:25][O:26][C:22]=2[CH:21]=1)[C:12]([O:14][CH2:15][CH3:16])=[O:13]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 2

HCID 131720122HCID 131720122, 화합물HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 131720123HCID 131720123, 화합물수율 67.1%

시약·촉매·용매 3

HCID 887Methanol촉매HCID 23938Palladium촉매HCID 8857Ethyl Acetate용매

실험 절차

The nitro compound of Example 18 (2.1 g, 5.42 mmol) is dissolved in 50 mL of ethyl acetate aided by a few drops of methanol. A catalytic amount of 20% palladium-on-carbon is added and the reaction mixture is stirred under one atmosphere of hydrogen at room temperature for 2 hours. The catalyst is removed by filtration through Celite and washed with ethyl acetate. The solvent is evaporated to provide 1.3 g (67%) of product as a thick oil;

후처리

  1. customThe catalyst is removed by filtration through Celite
  2. washwashed with ethyl acetate
  3. customThe solvent is evaporated

출처 및 근거

ORD 기록
ord-11c24f1f5e5b4972b794292892225657
출처 데이터셋
uspto-grants-1997_08
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05658943

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