4-(Pyridin-4-yl)butan-1-amine → 8-chloro-N-[4-(4-pyridinyl)butyl]dibenzo[b,f][1,4]thiazepine-10(11H)-carboxamide, monohydrochloride
반응식
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[S:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11](Cl)=[O:12])[C:4]=2[CH:3]=1.[N:20]1[CH:25]=[CH:24][C:23]([CH2:26][CH2:27][CH2:28][CH2:29][NH2:30])=[CH:22][CH:21]=1>>[ClH:1].[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[S:6][C:7]3[CH:17]=[CH:16][CH:15]=[CH:14][C:8]=3[CH2:9][N:10]([C:11]([NH:30][CH2:29][CH2:28][CH2:27][CH2:26][C:23]3[CH:22]=[CH:21][N:20]=[CH:25][CH:24]=3)=[O:12])[C:4]=2[CH:3]=1참가 물질
3
실험 절차
The title compound of Example 49 is reacted with the product of Example 23 by the method described in Example 18 to produce the free base of the title product. This material is converted to the title compound by the method described in Example 16.
출처 및 근거
- ORD 기록
- ord-30293482348f474487eb2f0bc78a5677
- 출처 데이터셋
- uspto-grants-1997_08