Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,8-Naphthyridine → 1,2,3,4-Tetrahydro-1,8-naphthyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,8-Naphthyridine | HCID 136069 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1,2,3,4-Tetrahydro-1,8-naphthyridine | HCID 13047367 | 100.9% |
반응 단계
1,8-Naphthyridine (1.0 g, 7.68 mmole) was hydrogenated (50 psi) with 10% Pd/C (100 mg) in absolute ethanol (40 mL) for 18 hr. The mixture was filtered through a pad of Celite® and the filtrate was concentrated to give the title compound (1.04 g) which was sufficiently pure for use in the next step: MS (ES) m/e 135 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07557125B2 |
| 출처 데이터셋 | uspto-grants-2009_07 |
| ORD ID | ord-82a58752556d48e6a1823e5f14201893 |
| 출처 메모 | uspto-grants-2009_07 |