Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
ethyl 1-methyl-1H-indole-2-carboxylate → N,1-Dimethyl-5-fluoro-1H-indole-2-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | ethyl 1-methyl-1H-indole-2-carboxylate | HCID 143368 | — |
| 반응물 | Ethyl 5-fluoro-1-methyl-1H-indole-2-carboxylate | HCID 10775338 | — |
| 생성물 | N,1-Dimethyl-5-fluoro-1H-indole-2-carboxamide | HCID 22593743 | 68% |
반응 단계
According to the procedure of Preparation 1(b), except substituting ethyl 5-fluoro-1-methyl-1H-indole-2-carboxylate for the ethyl 1-methyl-1H-indole-2-carboxylate, the title compound (2.1 g, 68%) was prepared as a white solid: MS (ES) m/e 207 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07557125B2 |
| 출처 데이터셋 | uspto-grants-2009_07 |
| ORD ID | ord-5937838202174a5190a842483394e586 |
| 출처 메모 | uspto-grants-2009_07 |