Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-(4-(3,5-Dichlorophenylureido)phenoxy)-2-methylpropionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | 3,5-Dichlorophenyl isocyanate | HCID 94460 | — |
| 반응물 | 2-(4-Aminophenoxy)-2-methylpropanoic acid | HCID 2774958 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 2-(4-(3,5-Dichlorophenylureido)phenoxy)-2-methylpropionic acid | HCID 195347 | — |
반응 단계
To a stirring solution of 4.95 g (0.025 mole) of 2-(4-aminophenoxy)-2-methylpropionic acid in 50 ml dry pyridine, 4.95 g (0.025 mole) of 3,5-dichlorophenyl isocyanate were added. After 1 hour stirring at room temperature, 150 ml water was added and the mixture was acidified with concentrated HCl. The precipitate was filtered, washed several times with cold water and dried. Recrystallization from aqueous acetone gave small plates 1.81 g (94%) MP 182°-184°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05472981 |
| 출처 데이터셋 | uspto-grants-1995_12 |
| ORD ID | ord-2609906c21db4039b75320cff996be04 |
| 출처 메모 | uspto-grants-1995_12 |