Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Buspirone Hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Buspirone | HCID 2477 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | Buspirone Hydrochloride | HCID 36431 | — |
반응 단계
treating the 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7,9-dione base with hydrogen chloride in ethanol or isopropanol under stirring at a temperature between 15° C. and 40° C. and isolating the 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7,9-dione hydrochloride melting at 188°-191° C., or
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05473072 |
| 출처 데이터셋 | uspto-grants-1995_12 |
| ORD ID | ord-e79e7eb33d48427385fab5eed245281c |
| 출처 메모 | uspto-grants-1995_12 |