Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Indenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Cerium(III) chloride | HCID 24636 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | 1H-inden-1-one | HCID 11815384 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Indenol | HCID 316919 | 99% |
반응 단계
The indenone from Example 109 (0.5 g) is reduced with NaBH4 (0.05 g) and cerium chloride (0.5 g) in methanol (20 ml). The reaction in ended after 10 minutes and the reaction mixture is poured into water. The pH is taken to 5 by means of dilute HCl and the mixture is extracted with ethyl acetate. It is washed with water and the solvent is evaporated. Indenol (0.49 g; m.p. 134° C.) is obtained (yield: 99%; compound no. 110).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05475132 |
| 출처 데이터셋 | uspto-grants-1995_12 |
| ORD ID | ord-8715c1e83d4b4fa1bfc24d12c01a77fc |
| 출처 메모 | uspto-grants-1995_12 |