Methyl Palmitate → N-(2,3-dihydroxypropyl)-N-dodecyl Hexadecanamide

HRID 2260085

반응식

HRID 2260085 반응식
[OH:1][CH:2]([CH2:17][OH:18])[CH2:3][NH:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[OH-].[K+].[C:21]([O:38]C)(=O)[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36]>>[OH:1][CH:2]([CH2:17][OH:18])[CH2:3][N:4]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[C:21](=[O:38])[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH3:36]

참가 물질

4

반응물 3

HCID 8181Methyl PalmitateHCID 14797Potassium HydroxideHCID 1024961,2-Propanediol, 3-(dodecylamino)-

생성물 1

HCID 10028839N-(2,3-dihydroxypropyl)-N-dodecyl Hexadecanamide

실험 절차

N-(2,3-dihydroxypropyl)-N-dodecylamine (0.50 g, 0.0019 mole) and potassium hydroxide (0.01 g, 0.18 mmole) were heated to 85° C. under vacuum. Methyl palmitate (0.57 g, 0.0021 mole) was heated and added dropwise to the reaction. The reaction was heated under vacuum for 6 hours. A waxy off-white solid was obtained (crude yield=0.92 g) The waxy solid was recrystalized from hot hexane (yield=0.6 g).

후처리

  1. additionadded dropwise to the reaction
  2. temperatureThe reaction was heated under vacuum for 6 hours
  3. customA waxy off-white solid was obtained (crude yield=0.92 g) The waxy solid
  4. customwas recrystalized from hot hexane (yield=0.6 g)

출처 및 근거

ORD 기록
ord-b11b42c77fe640e990fcaed9891e958c
출처 데이터셋
uspto-grants-1995_12
특허 번호
US05476671

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