참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Isobutyronitrile | HCID 6559 | — |
| 반응물 | Diphenylbismuthanyl Bromide | HCID 13026286 | — |
| 반응물 | Lithium diisopropylamine | HCID 45051747 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-Methyl-2-(diphenylbismuthanyl)-propionitrile | HCID 86616460 | — |
반응 단계
A 0.45 ml (5 mmole) of isobutyronitrile (Tokyo Kasei Co., Ltd.) was dissolved in 5 ml of THF, and the mixture was chilled to −78° C. under nitrogen atmosphere. Thereto was slowly added dropwise lithium diisopropylamine obtained above. The reaction mixture was stirred at −78° C. for 10 minutes and then heated to 0° C. Thereto was added dropwise a solution of 2.223 g (5 mmole) of diphenylbismuthanyl bromide prepared in Preparation Example 3 in 5 ml of THF.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07847043B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_12 |
|---|
| ORD ID | ord-ab5e418cd6464254a3f947294199fe83 |
|---|
| 출처 메모 | uspto-grants-2010_12 |
|---|
