Dichloromethane → HCID 73989400, 화합물
반응식
[C:1]1([NH:7][S:8]([C:11]2[CH:16]=[CH:15][C:14]([CH:17]=[CH:18][C:19]([OH:21])=O)=[CH:13][CH:12]=2)(=[O:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:22]CCl>CN(C)C=O>[C:1]1([NH:7][S:8]([C:11]2[CH:16]=[CH:15][C:14]([CH:17]=[CH:18][C:19]([Cl:22])=[O:21])=[CH:13][CH:12]=2)(=[O:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1참가 물질
4
반응 조건
- 온도
- 40 °C
실험 절차
To a suspension of 3-(4-phenylsulfamoyl-phenyl)-acrylic acid (43a) (0.25 g, 0.82 mmol) in dichloromethane (4.7 ml) oxalyl chloride (0.32 ml, 3.68 mmol) and one drop of dimethylformamide were added. The reaction mixture was stirred at 40° C. for one hour and concentrated under reduced pressure to give crude title compound (0.24 g, 92%).
후처리
- additionwere added
- concentrationconcentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-fb988d1bea7f4047945bbbaea2bf1e45
- 출처 데이터셋
- uspto-grants-2009_07
- 특허 번호
- US07557140B2
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