Methyl 4-methoxy-2-methylbenzoate → Methyl 4-hydroxy-2-methylbenzoate

반응식

COC(=O)C1C=C(O)C=CC=1CCC.[CH3:15][O:16][C:17](=[O:27])[C:18]1[CH:23]=[CH:22][C:21]([O:24]C)=[CH:20][C:19]=1[CH3:26]>>[CH3:15][O:16][C:17](=[O:27])[C:18]1[CH:23]=[CH:22][C:21]([OH:24])=[CH:20][C:19]=1[CH3:26]

참가 물질

반응물 2

HCID 13257269Methyl 4-methoxy-2-methylbenzoate

HCID 57443304HCID 57443304, 화합물

생성물 1

HCID 12351986Methyl 4-hydroxy-2-methylbenzoate수율 77%

실험 절차

The title compound (77%) is prepared essentially according to the preparation of 5-hydroxy-2-propyl-benzoic acid methyl ester using 4-methoxy-2-methyl-benzoic acid methyl ester. 1H NMR (400 MHz, CDCl3) δ 7.91-7.86 (m, 1H), 6.72-6.67 (m, 2H), 3.86 (s, 3H), 2.57 (s, 3H).

출처 및 근거

ORD 기록: ord-4dc682541de245f98e0ec8773c14bce9
출처 데이터셋: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07846960B2

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