Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl bromoacetate → (2-Acetyl-4-methoxy-phenoxy)-acetic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl bromoacetate | HCID 7748 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1-(2-Hydroxy-5-methoxyphenyl)ethan-1-one | HCID 69714 | — |
| 용매 | Methyl Ethyl Ketone | HCID 6569 | — |
| 생성물 | (2-Acetyl-4-methoxy-phenoxy)-acetic acid ethyl ester | HCID 15643798 | — |
반응 단계
A mixture of 16.6 g (100.0 mmol) of 2-hydroxi-5-methoxyacetophenone, 20 g (208 mmol) of potassium carbonate, 16.7 g (100.0 mmol) of ethyl bromoacetate and 200 ml of MEK is stirred at reflux temperature for 10 hr. The solids are filtered and the filtrate concentrated. The residue is suspended in water and the solid is filtered and dried. Yield: 10.2 g (40%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07557212B2 |
| 출처 데이터셋 | uspto-grants-2009_07 |
| ORD ID | ord-60bd36e5ee7d4e22abc36d0cbb75c24c |
| 출처 메모 | uspto-grants-2009_07 |