Selenium → 7-Methoxy-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one

HRID 226265

반응식

HRID 226265 반응식
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH2:16][CH2:15][C:10]3=[N:11][CH:12]=[CH:13][CH:14]=[C:9]3[C:8](=[O:17])[C:7]=2[CH:18]=1.[Se]>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[CH:16]=[CH:15][C:10]3=[N:11][CH:12]=[CH:13][CH:14]=[C:9]3[C:8](=[O:17])[C:7]=2[CH:18]=1

참가 물질

4

반응물 2

HCID 6326970SeleniumHCID 577544677-Methoxy-10,11-dihydro-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one

생성물 1

HCID 577544317-Methoxy-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one

시약·촉매·용매 1

HCID 1049Pyridine용매

반응 조건

온도
120 °C

실험 절차

A mixture of 2.3 g (9.6 mmol) of the product from Example 23 step 4, 1.85 g (16.6 mmol) of selenium dioxyde and 5 ml of pyridine is stirred at 120° C. for 6 hr. The whole is poured into excess petroleum ether and the solution is evaporated giving 0.55 g (24%) of enough pure title product as to prosecute with the synthesis.

후처리

  1. customthe solution is evaporated

출처 및 근거

ORD 기록
ord-927970835fe54928acc167750afbfec8
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07557212B2

연결된 노트

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