Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Pyrrolidinone, (4-aminophenyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 1-(4-Nitrophenyl)pyrrolidin-2-one | HCID 299328 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Pyrrolidinone, (4-aminophenyl)- | HCID 676146 | 92.5% |
반응 단계
A mixture of 1-(4-nitrophenyl)pyrrolidin-2-one (1.00 g, 4.85 mmol), 10% palladium on carbon (100 mg), methanol (20 ml) and tetrahydrofuran (20 ml) was stirred under hydrogen atmosphere for 12 hours, insoluble substances were removed by filtration, and the filtrate was concentrated to give 790 mg (92.5%) of the desired product as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07851473B2 |
| 출처 데이터셋 | uspto-grants-2010_12 |
| ORD ID | ord-e710ceef379b475083c097f649ae98ea |
| 출처 메모 | uspto-grants-2010_12 |