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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2263231생성일: 2026년 10월 25일

Methanol → Pyrrolidinone, (4-aminophenyl)-

https://huagongshe.com/reaction/2263231

반응식

참여 물질

역할이름HCID투입량
반응물MethanolHCID 887—
반응물1-(4-Nitrophenyl)pyrrolidin-2-oneHCID 299328—
촉매PalladiumHCID 23938—
용매TetrahydrofuranHCID 8028—
생성물Pyrrolidinone, (4-aminophenyl)-HCID 67614692.5%

반응 단계

A mixture of 1-(4-nitrophenyl)pyrrolidin-2-one (1.00 g, 4.85 mmol), 10% palladium on carbon (100 mg), methanol (20 ml) and tetrahydrofuran (20 ml) was stirred under hydrogen atmosphere for 12 hours, insoluble substances were removed by filtration, and the filtrate was concentrated to give 790 mg (92.5%) of the desired product as an oil.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07851473B2
출처 데이터셋uspto-grants-2010_12
ORD IDord-e710ceef379b475083c097f649ae98ea
출처 메모uspto-grants-2010_12