Methanol → N-(4-Aminophenyl)propanamide
반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11](=[O:14])[CH2:12][CH3:13])=[CH:6][CH:5]=1)([O-])=O.CO>[Pd].O1CCCC1>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:10][C:11](=[O:14])[CH2:12][CH3:13])=[CH:8][CH:9]=1참가 물질
5
실험 절차
A mixture of N-(4-nitrophenyl)propanamide (10 g, 51.5 mmol), 10% palladium on carbon (1 g), methanol (500 ml) and tetrahydrofuran (100 ml) was stirred under hydrogen atmosphere for 12 hours, insoluble substances were removed by filtration, and the filtrate was concentrated to give 8.00 g (94.8%) of the desired product as an oil.
후처리
- custominsoluble substances were removed by filtration
- concentrationthe filtrate was concentrated
출처 및 근거
- ORD 기록
- ord-1440103e8f404a808306c6bce395f453
- 출처 데이터셋
- uspto-grants-2010_12
- 특허 번호
- US07851473B2
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