Water → HCID 68780326, 화합물

HRID 2263314노트

반응식

HRID 2263314 반응식
[BrH:1].C(O)(=O)C.[Cl:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13](=O)[CH2:14][S:15][C:16]#[N:17].O>C(O)(=O)C>[Br:1][C:16]1[S:15][CH:14]=[C:13]([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[Cl:6])[N:17]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 21893785Acetic Acid Mixture with Hydrobromic AcidHCID 242137572-(2-Chlorophenyl)-2-oxoethyl thiocyanate

생성물 1

HCID 68780326HCID 68780326, 화합물수율 67.1%

시약·촉매·용매 1

HCID 176Acetic Acid용매

반응 조건

온도
130 °C

실험 절차

A 25% hydrogen bromide/acetic acid (50 ml) solution was added to a solution of 2-(2-chlorophenyl)-2-oxoethyl thiocyanate (5.15 g, 24.3 mmol) in acetic acid (50 ml), and the mixture was stirred at 130° C. for 2 hours. Water (100 ml) was poured to the reaction mixture, and crystals were collected by filtration and washed with water to give 4.48 g (67.1%) of the desired product as a solid.

후처리

  1. filtrationwere collected by filtration
  2. washwashed with water

출처 및 근거

ORD 기록
ord-2f701d08443a4b278a87953a1468c993
출처 데이터셋
uspto-grants-2010_12
특허 번호
US07851473B2

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