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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2263961생성일: 2026년 10월 26일

Phosgene → rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-[2-ethoxy-4-(1-hydroxy-1-methyl-ethyl)-phenyl]-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride

https://huagongshe.com/reaction/2263961

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참여 물질

역할이름HCID투입량
반응물PhosgeneHCID 6371—
반응물rac-2-{4-[(4S*,5R*)-4,5-Bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazol-2-yl]-3-ethoxy-phenyl}-propan-2-olHCID 17754634—
용매TriethylamineHCID 8471—
생성물rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-[2-ethoxy-4-(1-hydroxy-1-methyl-ethyl)-phenyl]-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 73408763—

반응 단계

In a manner analogous to the method described in example 3, rac-2-{4-[(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazol-2-yl]-3-ethoxy-phenyl}-propan-2-ol was reacted with phosgene in the presence of triethylamine to give the title compound.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07851626B2
출처 데이터셋uspto-grants-2010_12
ORD IDord-448455874a4441018cd0acac35b5c9c1
출처 메모uspto-grants-2010_12