Phosgene → rac-(4S,5R)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride

참여 물질

역할	이름	HCID	투입량
반응물	Phosgene	HCID 6371	—
반응물	rac-(4S,5R)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole	HCID 68685099	—
용매	Triethylamine	HCID 8471	—
생성물	rac-(4S,5R)-4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl chloride	HCID 73408764	—

반응 단계

In a manner analogous to the method described in example 3, rac-(4S*,5R*)-4,5-bis-(4-chloro-phenyl)-2-(2-ethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole was reacted with phosgene in the presence of triethylamine to give the title compound.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07851626B2
출처 데이터셋	uspto-grants-2010_12
ORD ID	ord-8c57ab80e14e42d287ceb005d905ce04
출처 메모	uspto-grants-2010_12