5-((6-Chloropyrimidin-4-yl)oxy)-1H-indole → 5-[(2-chloro-4-pyrimidinyl)oxy]-2,3-dihydro-1H-indole

HRID 2264563

반응식

HRID 2264563 반응식
[Cl:1][C:2]1[N:7]=[C:6]([O:8][C:9]2[CH:10]=[C:11]3[C:15](=[CH:16][CH:17]=2)[NH:14][CH:13]=[CH:12]3)[CH:5]=[CH:4][N:3]=1.ClC1N=CN=C(OC2C=C3C(=CC=2)NC=C3)C=1>>[Cl:1][C:2]1[N:7]=[C:6]([O:8][C:9]2[CH:10]=[C:11]3[C:15](=[CH:16][CH:17]=2)[NH:14][CH2:13][CH2:12]3)[CH:5]=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 574551565-((6-Chloropyrimidin-4-yl)oxy)-1H-indoleHCID 577373465-(2-chloropyrimidin-4-yloxy)-1H-indole

생성물 1

HCID 866182855-[(2-chloro-4-pyrimidinyl)oxy]-2,3-dihydro-1H-indole

실험 절차

Utilising a similar procedure, but employing 5-[(2-chloro-4-pyrimidinyl)oxy]-1H-indole in lieu of 5-[(6-chloro-4-pyrimidinyl)oxy]-1H-indole afforded 5-[(2-chloro-4-pyrimidinyl)oxy]-2,3-dihydro-1H-indole, as an oil.

출처 및 근거

ORD 기록
ord-abc28d08649e4a51996233c8249f7559
출처 데이터셋
uspto-grants-2010_12
특허 번호
US07855215B2

연결된 노트

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