2-(3-Bromopropoxy)tetrahydro-2H-pyran → HCID 10203347, 화합물

HRID 2265331노트

반응식

HRID 2265331 반응식
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11]([CH:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH2:16][CH2:15][CH2:14]2)=[O:12])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[O:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH:24]1[O:29][CH2:30][CH2:31][CH2:32]Br>>[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]([CH2:32][CH2:31][CH2:30][O:29][CH:24]2[CH2:25][CH2:26][CH2:27][CH2:28][O:23]2)[C:11]([CH:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH2:16][CH2:15][CH2:14]2)=[O:12])=[CH:6][CH:5]=1)([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 27779882-(3-Bromopropoxy)tetrahydro-2H-pyranHCID 17854222HCID 17854222, 화합물

생성물 1

HCID 10203347HCID 10203347, 화합물

실험 절차

By the reaction and treatment in the same manner as in Example 6 using N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.75 g) and 3-(tetrahydropyran-2-yloxy)propyl bromide (0.52 mL) as starting materials, N-(4-isopropylphenyl)-N-[3-(tetrahydropyran-2-yloxy)propyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.9 g) was obtained.

출처 및 근거

ORD 기록
ord-68ca9e6dfb88439da2c0ef0760cd135a
출처 데이터셋
uspto-grants-2010_12
특허 번호
US07855297B2

반응 노트

불러오는 중…