HCID 178515200, 화합물 → HCID 178515212, 화합물

반응식

[C:1]1([N:7]2[C:25](=[O:26])[C:10]3=[CH:11][NH:12][C:13]4[CH:14]=[CH:15][C:16]([N:19]5[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]5)=[N:17][C:18]=4[C:9]3=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3]C=1.FC1C=CC2NC=C3C(=O)N(C4C=CC=CN=4)N=C3C=2[N:29]=1>>[N:19]1([C:16]2[CH:15]=[CH:14][C:13]3[NH:12][CH:11]=[C:10]4[C:25](=[O:26])[N:7]([C:1]5[CH:6]=[CH:5][CH:4]=[CH:3][N:29]=5)[N:8]=[C:9]4[C:18]=3[N:17]=2)[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]1

참가 물질

반응물 2

HCID 178515200HCID 178515200, 화합물

HCID 178515211HCID 178515211, 화합물

생성물 1

HCID 178515212HCID 178515212, 화합물

실험 절차

The title compound was prepared following the procedure described for 6a using 5b instead of 5a. 1H-NMR (CDCl3) δ (ppm): 2.97 (4H, br), 3.72 (4H, br), 6.82 (1H, d, J=9.34 Hz), 7.42 (4H, m), 7.75 (1H, m), 8.17 (2H, d, J=7.97 Hz), 8.52 (1H, s). m/z 348.4 (MH+).

출처 및 근거

ORD 기록: ord-66ed53f5c48a496ea147611d19afec72
출처 데이터셋: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07858614B2

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