HCID 59382877, 화합물 → HCID 59383036, 화합물

HRID 2266206노트

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HRID 2266206 반응식
[F:1][C:2]([F:25])([F:24])[C:3]([CH:11]1[CH2:16][CH2:15][CH2:14][N:13](C(OC(C)(C)C)=O)[CH2:12]1)([OH:10])[CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH3:9]>C(O)(C(F)(F)F)=O.ClCCl>[F:25][C:2]([F:1])([F:24])[C:3]([CH:11]1[CH2:16][CH2:15][CH2:14][NH:13][CH2:12]1)([OH:10])[CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH3:9]

참가 물질

3

반응물 1

HCID 59382877HCID 59382877, 화합물

생성물 1

HCID 59383036HCID 59383036, 화합물

시약·촉매·용매 1

HCID 21863450Trifluoroacetic acid methylene chloride용매

실험 절차

Tert-butyl 3-(1,1,1-trifluoro-2-hydroxy-6-methoxyhexan-2-yl)piperidine-1-carboxylate (20 mg) was dissolved in 1:1 TFA/dichloromethane (4 mL). The mixture was stirred for 30 min. The mixture was concentrated to afford 1,1,1-trifluoro-6-methoxy-2-(piperidin-3-yl)hexan-2-ol which was used without purification.

후처리

  1. concentrationThe mixture was concentrated

출처 및 근거

ORD 기록
ord-60d7364df42048a0a6780457a19299ab
출처 데이터셋
uspto-grants-2010_12
특허 번호
US07858624B2

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