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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2266623생성일: 2026년 10월 26일

(S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl ester → (S)-2-{3-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy}propionic Acid Methyl Ester

https://huagongshe.com/reaction/2266623

반응식

참여 물질

역할이름HCID투입량
반응물(S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl esterHCID 66717596—
반응물2-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-3-oxopentanoic Acid Ethyl EsterHCID 68784675—
생성물(S)-2-{3-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-2-ethyl-8-fluoro-4-oxo-1,4-dihydroquinolin-5-yloxy}propionic Acid Methyl EsterHCID 68782627—

반응 단계

The title compound was prepared by the method of Preparation 65c using 2-[2-chloro-4-(pyrrolidine-1-carbonyl)benzyl]-3-oxopentanoic acid ethyl ester and (S)-2-(3-amino-4-fluorophenoxy)propionic acid methyl ester.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07858640B2
출처 데이터셋uspto-grants-2010_12
ORD IDord-f1baca9cfb1c442182784ef2555eeb36
출처 메모uspto-grants-2010_12