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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 226700생성일: 2026년 10월 25일

1,4-Benzodioxan-6-ylamine → N2-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(2-hydro xy-2-phenylethyl)-2,4-pyrimidinediamine

https://huagongshe.com/reaction/226700

반응식

참여 물질

역할이름HCID투입량
반응물1,4-Benzodioxan-6-ylamineHCID 89148—
반응물N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-primidinediamineHCID 22060334—
반응물2-chloro-5-fluoro-N4-(2-hydroxy-2-phenylethyl)-4-pyrimidineamineHCID 22060827—
생성물N2-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(2-hydro xy-2-phenylethyl)-2,4-pyrimidinediamineHCID 22060669—

반응 단계

In a manner similar to the preparation of N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine, 2-chloro-5-fluoro-N4-(2-hydroxy-2-phenylethyl)-4-pyrimidineamine and 3,4-ethylenedioxyaniline were reacted to yield N2-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(2-hydroxy-2-phenylethyl)-2,4-pyrimidinediamine.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07557210B2
출처 데이터셋uspto-grants-2009_07
ORD IDord-0f20c43f67914c2ab846aa746d95d6eb
출처 메모uspto-grants-2009_07