Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-4-cyanopyridine → 2-{[3-(Hydroxymethyl)phenyl]sulfanyl}pyridine-4-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-4-cyanopyridine | HCID 568638 | — |
| 반응물 | (3-Sulfanylphenyl)methanol | HCID 12813879 | — |
| 생성물 | 2-{[3-(Hydroxymethyl)phenyl]sulfanyl}pyridine-4-carbonitrile | HCID 57355460 | 63% |
반응 단계
Using the method of Preparation 155 using (3-mercaptophenyl)methanol (6.00 g, 42.8 mmol) and 2-chloroisonicotinonitrile (5.65 g, 40.8 mmol) affords the title compound (6.22 g, 63%): 243 (M+H, 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07858646B2 |
| 출처 데이터셋 | uspto-grants-2010_12 |
| ORD ID | ord-fbdd8d9bcd8b49b0b4efc5c1269dd9f1 |
| 출처 메모 | uspto-grants-2010_12 |