1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochloride → 4-(2,2-Dimethyl-propoxy)-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide
반응식
[CH3:1][C:2]([CH3:18])([CH3:17])[CH2:3][O:4][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[CH:7]=[C:8]([C:14]([OH:16])=O)[NH:9]2.Cl.Cl.Cl.[N:22]1([CH2:29][CH2:30][N:31]2[CH2:36][CH2:35][CH:34]([NH2:37])[CH2:33][CH2:32]2)[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[N:22]1([CH2:29][CH2:30][N:31]2[CH2:32][CH2:33][CH:34]([NH:37][C:14]([C:8]3[NH:9][C:10]4[C:6]([CH:7]=3)=[C:5]([O:4][CH2:3][C:2]([CH3:1])([CH3:18])[CH3:17])[CH:13]=[CH:12][CH:11]=4)=[O:16])[CH2:35][CH2:36]2)[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1참가 물질
3
실험 절차
This compound is synthesized analogously to Example 1 from 4-(2,2-Dimethyl-propoxy)-1H-indole-2-carboxylic acid 85 (preparation see below) and amine 5.
출처 및 근거
- ORD 기록
- ord-62e8e51fe8eb4ef186fe1e9142dfbc61
- 출처 데이터셋
- uspto-grants-2010_12