Lupinine → HCID 59600128, 화합물

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[NH:1]1[CH2:6][CH2:5][CH:4]([NH:7][C:8]([C:10]2[NH:11][C:12]3[C:17]([CH:18]=2)=[C:16]([O:19][CH2:20][CH:21]2[CH2:24][CH2:23][CH2:22]2)[CH:15]=[CH:14][CH:13]=3)=[O:9])[CH2:3][CH2:2]1.[C@H:25]1([CH2:35]O)[C@@H:34]2[N:29]([CH2:30][CH2:31][CH2:32][CH2:33]2)[CH2:28][CH2:27][CH2:26]1>>[C@H:25]1([CH2:35][N:1]2[CH2:6][CH2:5][CH:4]([NH:7][C:8]([C:10]3[NH:11][C:12]4[C:17]([CH:18]=3)=[C:16]([O:19][CH2:20][CH:21]3[CH2:24][CH2:23][CH2:22]3)[CH:15]=[CH:14][CH:13]=4)=[O:9])[CH2:3][CH2:2]2)[C@@H:34]2[N:29]([CH2:30][CH2:31][CH2:32][CH2:33]2)[CH2:28][CH2:27][CH2:26]1

참가 물질

반응물 2

HCID 91461Lupinine

HCID 66841515HCID 66841515, 화합물

생성물 1

HCID 59600128HCID 59600128, 화합물

실험 절차

This compound is synthesized from 4-cyclobutylmethoxy-1H-indole-2-carboxylic acid piperidin-4-ylamide, 162 (preparation see below) and (1R,9aR)-1-(octahydro-quinolizin-1-yl)-methanol analogously to the method described in example 127.

출처 및 근거

ORD 기록: ord-bffcc506320f4179816430920faae1f5
출처 데이터셋: uspto-grants-2010_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07858781B2

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