3-Chloro-4-methoxyaniline → N,N'-bis(3-chloro-4-methoxyphenyl)-5-fluoropyrimidine-2,4-diamine

HRID 226892노트

반응식

HRID 226892 반응식
Cl[C:2]1[N:7]=[C:6](Cl)[C:5]([F:9])=[CH:4][N:3]=1.[Cl:10][C:11]1[CH:12]=[C:13]([CH:15]=[CH:16][C:17]=1[O:18][CH3:19])[NH2:14]>>[Cl:10][C:11]1[CH:12]=[C:13]([NH:14][C:2]2[N:7]=[C:6]([NH:14][C:13]3[CH:15]=[CH:16][C:17]([O:18][CH3:19])=[C:11]([Cl:10])[CH:12]=3)[C:5]([F:9])=[CH:4][N:3]=2)[CH:15]=[CH:16][C:17]=1[O:18][CH3:19]

참가 물질

3

반응물 2

HCID 214413-Chloro-4-methoxyanilineHCID 2507052,4-Dichloro-5-fluoropyrimidine

생성물 1

HCID 1266496N,N'-bis(3-chloro-4-methoxyphenyl)-5-fluoropyrimidine-2,4-diamine

실험 절차

In a like manner to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, 2,4-dichloro-5-fluoropyrimidine and 3-chloro-4-methoxyaniline were reacted to provide N2,N4-Bis(3-chloro-4-methoxyphenyl)-5-fluoro-2,4-pyrimidinediamine.

후처리

  1. customwere reacted

출처 및 근거

ORD 기록
ord-49452b617dea4a4491a4cf5703bbac34
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07557210B2

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