3,4-Dichlorophenyl isocyanate → 2-[1-(1-(3,4-Dichlorophenylcarbamoyl)piperidin-3-yl)ethylamino]-4-[benzimidazol-1-yl]pyrimidine
반응식
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH:7]([NH:9][C:10]2[N:15]=[C:14]([N:16]3[C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=4[N:18]=[CH:17]3)[CH:13]=[CH:12][N:11]=2)[CH3:8])[CH2:2]1.[Cl:25][C:26]1[CH:27]=[C:28]([N:33]=[C:34]=[O:35])[CH:29]=[CH:30][C:31]=1[Cl:32]>>[Cl:25][C:26]1[CH:27]=[C:28]([NH:33][C:34]([N:1]2[CH2:6][CH2:5][CH2:4][CH:3]([CH:7]([NH:9][C:10]3[N:15]=[C:14]([N:16]4[C:20]5[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=5[N:18]=[CH:17]4)[CH:13]=[CH:12][N:11]=3)[CH3:8])[CH2:2]2)=[O:35])[CH:29]=[CH:30][C:31]=1[Cl:32]참가 물질
3
실험 절차
The title compound was prepared from 2-[1-(piperidin-3-yl)-ethylamino]-4-[benzimidazol-1-yl]pyrimidine and 3,4-dichlorophenylisocyanate according to the procedure described in EXAMPLE 29. Mass spectrum (ESI) 510.3 (M+).
출처 및 근거
- ORD 기록
- ord-6bbf75b8839441b6963f67b625680fa9
- 출처 데이터셋
- uspto-grants-2001_12