(2S,3S)-tert-Butyl 3-amino-2-phenylpiperidine-1-carboxylate → (2S,3S)-1-tert-Butoxycarbonyl-3-[5-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-2-methoxybenzyl]amino-2-phenylpiperidine

반응식

FC(F)=C(C1C=CC(OC)=C(C=1)C=O)C(F)(F)F.N[C@H]1CCCN(C(OC(C)(C)C)=O)[C@H]1C1C=CC=CC=1.[C:39]([O:43][C:44]([N:46]1[CH2:51][CH2:50][CH2:49][C@H:48]([NH:52][CH2:53][C:54]2[CH:59]=[C:58]([CH:60]([C:65](F)([F:67])[F:66])[C:61]([F:64])([F:63])[F:62])[CH:57]=[CH:56][C:55]=2[O:69][CH3:70])[C@@H:47]1[C:71]1[CH:76]=[CH:75][CH:74]=[CH:73][CH:72]=1)=[O:45])([CH3:42])([CH3:41])[CH3:40]>>[C:39]([O:43][C:44]([N:46]1[CH2:51][CH2:50][CH2:49][C@H:48]([NH:52][CH2:53][C:54]2[CH:59]=[C:58]([C:60]([C:61]([F:62])([F:63])[F:64])=[C:65]([F:66])[F:67])[CH:57]=[CH:56][C:55]=2[O:69][CH3:70])[C@@H:47]1[C:71]1[CH:72]=[CH:73][CH:74]=[CH:75][CH:76]=1)=[O:45])([CH3:42])([CH3:40])[CH3:41]