3-(2-Amino-4,5-dimethoxyphenyl)-2-methyl-2-propenoic acid ethyl ester → 6,7-Dimethoxy-3-methyl-carbostyril

HRID 2269781노트

반응식

HRID 2269781 반응식
C([O:3][C:4](=O)[C:5]([CH3:18])=[CH:6][C:7]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([O:15][CH3:16])=[CH:9][C:8]=1[NH2:17])C>C(O)C>[CH3:14][O:13][C:11]1[CH:12]=[C:7]2[C:8](=[CH:9][C:10]=1[O:15][CH3:16])[NH:17][C:4](=[O:3])[C:5]([CH3:18])=[CH:6]2

참가 물질

3

반응물 1

HCID 702131123-(2-Amino-4,5-dimethoxyphenyl)-2-methyl-2-propenoic acid ethyl ester

생성물 1

HCID 183480236,7-Dimethoxy-3-methyl-carbostyril수율 92%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Into 30 ml of ethyl alcohol, 0.5 g of 3-(2-amino-4,5-dimethoxyphenyl)-2-methyl-2-propenoic acid ethyl ester was dissolved. This solution was irradiated with ultraviolet rays at 365 nm for about 20 hours, and the precipitated crystal was filtered out. This crystal was recrystallized from ethanol, whereby 0.38 g of the aimed compound was obtained (yield: 92%).

후처리

  1. customThis solution was irradiated with ultraviolet rays at 365 nm for about 20 hours
  2. filtrationthe precipitated crystal was filtered out
  3. customThis crystal was recrystallized from ethanol

출처 및 근거

ORD 기록
ord-d163b67745eb45f392d832254474f72a
출처 데이터셋
uspto-grants-2001_12
특허 번호
US06329546B1

반응 노트

불러오는 중…