Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Amino-4-picoline → 3-(3,4-Dimethyl-benzoyl)-8-methyl-1H-[1,5]naphthyridin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Amino-4-picoline | HCID 137935 | — |
| 반응물 | 2-(3,4-Dimethyl-benzoyl)-3-methoxy-acrylic acid methyl ester | HCID 66879272 | — |
| 용매 | Diphenyl Ether | HCID 7583 | — |
| 생성물 | 3-(3,4-Dimethyl-benzoyl)-8-methyl-1H-[1,5]naphthyridin-4-one | HCID 57754561 | 16.1% |
반응 단계
Experimental conditions analogous to those described for Step 1 of Example 1 were used with 0.50 g (2.01 mmol) 2-(3,4-Dimethyl-benzoyl)-3-methoxy-acrylic acid methyl ester, 0.22 g (2.01 mmol) of 4-Methyl-pyridin-3-ylamine, and 30 mL of diphenyl ether to yield 94.4 mg of 3-(3,4-Dimethyl-benzoyl)-8-methyl-1H-[1,5]naphthyridin-4-one as a brown solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07557213B2 |
| 출처 데이터셋 | uspto-grants-2009_07 |
| ORD ID | ord-737a50d3f24547abb218a569d40486d7 |
| 출처 메모 | uspto-grants-2009_07 |