2-Bromopropane → 5-(Bromomethyl)-2-(difluoromethoxy)-3-(3-isopropoxyphenyl)pyridine

HRID 2271467노트

반응식

HRID 2271467 반응식
[Br:1][CH2:2][C:3]1[CH:4]=[C:5]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH:20]3[CH2:23]O[CH2:21]3)[CH:14]=2)[C:6]([O:9][CH:10]([F:12])[F:11])=[N:7][CH:8]=1.BrC(C)C>>[Br:1][CH2:2][C:3]1[CH:4]=[C:5]([C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH:20]([CH3:23])[CH3:21])[CH:14]=2)[C:6]([O:9][CH:10]([F:12])[F:11])=[N:7][CH:8]=1

참가 물질

3

반응물 2

HCID 63582-BromopropaneHCID 904149725-(Bromomethyl)-2-(difluoromethoxy)-3-(3-(oxetan-3-yloxy)phenyl)pyridine

생성물 1

HCID 904153115-(Bromomethyl)-2-(difluoromethoxy)-3-(3-isopropoxyphenyl)pyridine

실험 절차

The title compound was prepared in a manner analogous to Intermediate 10, using 2-bromopropane for step 2, followed by bromination according to step 3. [M-FI-1]=373.24.

출처 및 근거

ORD 기록
ord-1f3934082a5c4c53830b72a576ef7ec5
출처 데이터셋
uspto-grants-2015_09
특허 번호
US09120770B2

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