3-(2-(Dimethylamino)ethyl)aniline → HCID 66715828, 화합물
반응식
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][C:6]([C:12]([CH:14]1[CH2:16][CH2:15]1)=[O:13])=[C:5]2Cl.[CH3:18][N:19]([CH3:29])[CH2:20][CH2:21][C:22]1[CH:23]=[C:24]([CH:26]=[CH:27][CH:28]=1)[NH2:25]>>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][C:6]([C:12]([CH:14]1[CH2:16][CH2:15]1)=[O:13])=[C:5]2[NH:25][C:24]1[CH:26]=[CH:27][CH:28]=[C:22]([CH2:21][CH2:20][N:19]([CH3:18])[CH3:29])[CH:23]=1참가 물질
3
실험 절차
Following general procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (280 mg, 0.91 mmol) was reacted with 3-[2-(dimethylamino)ethyl]aniline (150 mg, 0.91 mmol) to afford the desired product (270 mg, 68%) as a yellow solid: ESI MS m/z 438 [C23H24BrN3O+H]+.
출처 및 근거
- ORD 기록
- ord-674561472643496b8e8180898ec1d577
- 출처 데이터셋
- uspto-grants-2015_09
- 특허 번호