Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole → 3-(4-Piperidinyl)-1H-indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole | HCID 2761023 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-(4-Piperidinyl)-1H-indole | HCID 702235 | — |
반응 단계
19.03 g (0.096 mol) of 3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole were hydrogenated in a Parr apparatus during 18 h at 3 bar with 2.2 g of Pd/C 10% in 600 ml of methanol. After standard work-up, 16.76 g (87% of yield) of the desired product were obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07560471B2 |
| 출처 데이터셋 | uspto-grants-2009_07 |
| ORD ID | ord-82f1ca6314c24c078bf152d40688e60d |
| 출처 메모 | uspto-grants-2009_07 |