2-Methoxyethylamine → N-(2-Methoxyethyl)-2-nitroaniline
반응식
[CH3:1][O:2][CH2:3][CH2:4][NH2:5].F[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N+:13]([O-:15])=[O:14]>C(O)C>[CH3:1][O:2][CH2:3][CH2:4][NH:5][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N+:13]([O-:15])=[O:14]참가 물질
4
실험 절차
2-methoxyethaneamine (3 mL) is added to a solution of 1-fluoro-2-nitrobenzene (400 mg, 2.84 mmol) in ethanol. The reaction may be stirred at room temperature for an appropriate time period (such as overnight) and concentrated. The residue may be purified by any appropriate method including Biotage column chromatography to give N-(2-methoxyethyl)-2-nitroaniline (477 mg).
후처리
- customThe reaction
- concentrationconcentrated
- customThe residue may be purified by any appropriate method
출처 및 근거
- ORD 기록
- ord-ea8506d4311a492ba5cc7a4ca47f8f31
- 출처 데이터셋
- uspto-grants-2015_09
- 특허 번호
- US09125901B2
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